BDBM50561038 CHEMBL4752307::US11420984, Example 7

SMILES N[C@H]1CN[C@](CCCCB(O)O)(C1)C(O)=O

InChI Key InChIKey=SHQWTXRBVVLSOY-VXNVDRBHSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50561038   

TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  10nMAssay Description:Inhibition of human Arg1 by TOGA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human Arg1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Arg2 by TOGA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  20nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  1.66E+4nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  10nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561038(CHEMBL4752307 | US11420984, Example 7)
Affinity DataIC50:  6.41E+3nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent