BDBM50561481 CHEMBL4746074
SMILES CC(C#Cc1cccc(c1)C(=O)NCc1ccc(F)cc1C(F)(F)F)N(O)C(N)=O
InChI Key InChIKey=UIZHRZKRHLDEEW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50561481
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt
Curated by ChEMBL
Goethe-University Of Frankfurt
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Of Frankfurt
Curated by ChEMBL
Goethe-University Of Frankfurt
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair