BDBM50561764 CHEMBL4743180
SMILES CNC(=O)NC1CCN(CC1)C(=O)[C@@H](CCCCN)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC[C@H](C)c1ccccc1
InChI Key InChIKey=POEKRJYEMCDIMO-SPYAMJAOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50561764
TargetKappa-type opioid receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 0.00100nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation measured afte...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human delta opioid receptor assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human mu opioid receptor assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2 in human pooled liver microsomes using phenacetin as substrate measured up to 20 mins by UHPLC-MS/MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 in human pooled liver microsomes using dextromethorphan as substrate measured up to 20 mins by UHPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 in human pooled liver microsomes using midazolam as substrate measured up to 20 mins by UHPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 in human pooled liver microsomes using testosterone as substrate measured up to 20 mins by UHPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19 in human pooled liver microsomes using S-mephenytoin as substrate measured up to 20 mins by UHPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9 in human pooled liver microsomes using tolbutamide as substrate measured up to 20 mins by UHPLC-MS/MS analysisMore data for this Ligand-Target Pair