BDBM50562002 CHEMBL4795980
SMILES [H][C@]12Cc3c(nc(nc3N3CCOC[C@H]3C)-c3nc(N)ns3)N1CCOC2
InChI Key InChIKey=IEQDPVIZBYEBGM-NXEZZACHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50562002
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to recombinant N-terminal GST-fused mTOR (1360 to 2549 residues) (unknown origin) by ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKi: 806nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to recombinant N-terminal His6-tagged p110alpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 261nMAssay Description:Inhibition of mTORC1 in human A2058 cells assessed as reduction in S6 ribosomal protein phosphorylation at Ser235/236 residues incubated for 1 hr by ...More data for this Ligand-Target Pair