BDBM50562158 CHEMBL4747585

SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2ccccc2)cc1

InChI Key InChIKey=SYKQOVVZSRWKHB-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50562158   

TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataKi:  27nMAssay Description:Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataIC50:  868nMAssay Description:Inhibition of MAGL in human U937 cells assessed as reduction in [3H]glycerol formation using [1,2,3-3H]2-OG as substrate incubated for 15 mins by liq...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using [3H]2-OG as substrate preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor incubated for 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells assessed as reduction in [3H]ethanolamine formation using [ethanolamine-1-3H]AEA as substrate incubated for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor incubated for 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate incubated for 30 mins by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562158(CHEMBL4747585)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using [3H]2-OG as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed