BDBM50562747 CHEMBL4756814

SMILES CCc1nc2c(nccc2n1S(=O)(=O)c1cccc(Cl)c1)N1CCNCC1

InChI Key InChIKey=GATDTMAYFGZGAV-UHFFFAOYSA-N

Data  5 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50562747   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50562747(CHEMBL4756814)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50562747(CHEMBL4756814)
Affinity DataKi:  146nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50562747(CHEMBL4756814)
Affinity DataKi:  562nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT2A expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50562747(CHEMBL4756814)
Affinity DataKi:  886nMAssay Description:Displacement of [3H]-raclopride from human D2L expressed in CHO-K1 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50562747(CHEMBL4756814)
Affinity DataKi:  3.76E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7b expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50562747(CHEMBL4756814)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human 5HT1A expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by LANCE ultra cAMP detect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50562747(CHEMBL4756814)
Affinity DataIC50:  5.40nMAssay Description:Neutral antagonist activity at 5HT6R (unknown origin) expressed in 1321N1 cells co-expressing CAMYEL assessed as inhibition of WAY181187-induced cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed