BDBM50563855 CHEMBL4780641
SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC4(CN(C)c5ccccc45)CC3)cc2)cc1
InChI Key InChIKey=QRCCYPSGLCYDNW-NDEPHWFRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50563855
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 56nMAssay Description:Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...More data for this Ligand-Target Pair
Affinity DataKd: 9.5nMAssay Description:Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...More data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu...More data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair