BDBM50564595 CHEMBL4790322
SMILES CC(C)(O)c1cc(Nc2cc(Oc3cn(nc3-c3ccc(cc3)C#N)C3CC3)ccn2)ccn1
InChI Key InChIKey=BMFDPTZPMFMHEN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50564595
Affinity DataIC50: 162nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of ALK5 (unknown origin) measured after 120 mins of incubation by ADP-Glo kinase assayMore data for this Ligand-Target Pair