BDBM50564600 CHEMBL4784607

SMILES Cc1noc(C)c1-c1nn(cc1Oc1ccnc(Nc2ccnc(c2)C(C)(C)O)c1)C1CC1

InChI Key InChIKey=HAFVCEITTXVVHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564600   

TargetTGF-beta receptor type-1(Mus musculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564600(CHEMBL4784607)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564600(CHEMBL4784607)
Affinity DataIC50:  6.74E+3nMAssay Description:Inhibition of ALK5 (unknown origin) measured after 120 mins of incubation by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed