BDBM50565316 CHEMBL4776121

SMILES O[C@H](c1ccnc(Nc2ccc(cc2)C#N)n1)c1ccc(cc1Cl)-c1ccc(cc1)C#N

InChI Key InChIKey=LRGUYOVPBIAHKP-DEOSSOPVSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50565316   

TargetReverse transcriptase(Human immunodeficiency virus 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565316(CHEMBL4776121)
Affinity DataEC50:  53nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565316(CHEMBL4776121)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565316(CHEMBL4776121)
Affinity DataEC50:  3nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565316(CHEMBL4776121)
Affinity DataEC50:  128nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565316(CHEMBL4776121)
Affinity DataEC50:  14nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed