BDBM50566951 CHEMBL4875929
SMILES CCc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)nc3cccc(C)c23)n[nH]1
InChI Key InChIKey=AZCHQQLGTDJHFL-ZDUSSCGKSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50566951
TargetG protein-coupled receptor kinase 6(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant full-length human GRK6 using casein as substrate measured after 80 mins in presence of [gamma33P]ATP by radiometric scintil...More data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 6(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Binding affinity to FLAG-tagged GRK6 in human KMS11 cells incubated for 2.5 hrs by ITDR assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Ontario Institute For Cancer Research
Curated by ChEMBL
Ontario Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human IGF-1R (959 to end residues) using KKKSPGEYVNIEF as substrate incubated for 40 mins in presence of [gamma-33ATP] by r...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant full length human Aurora A using LRRASLG as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometric sci...More data for this Ligand-Target Pair