BDBM50567652 CHEMBL4878693

SMILES COc1ccc(cc1)C(=O)C=CNc1cc(nn1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=CUVLPOCXZYLQBD-MSUUIHNZSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50567652   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataKi:  25nMAssay Description:Inhibition of CDK2/Cyclin A2 (unknown origin) after 10 mins by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataKi:  208nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataKi:  581nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataKi:  9.12E+3nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataIC50:  42nMAssay Description:Inhibition of CDK2/Cyclin A2 (unknown origin) after 10 mins by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataIC50:  326nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50567652(CHEMBL4878693)
Affinity DataIC50:  955nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed