BDBM50568920 CHEMBL4846823
SMILES CC1(CCCN2CCN(CC2)c2ccccn2)Cc2cc(Cl)ccc2C1=O
InChI Key InChIKey=AKXPLUFJRRUGNE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50568920
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.741nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.45E+3nMAssay Description:Displacement of [3H]-Mesulergine from human 5-HT2C receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.45E+3nMAssay Description:Displacement of [3H]-Mesulergine from human 5-HT2C receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Florida A&M University
Curated by ChEMBL
Florida A&M University
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-citalopram from human SERT receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Florida A&M University
Curated by ChEMBL
Florida A&M University
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]-citalopram from human SERT receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: >10nMAssay Description:Agonist activity at human 5-HT7A receptor expressed in HEK cell membranes incubated for 20 mins by cAMP functional assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human 5-HT7A receptor expressed in HEK cell membranes assessed as reduction in serotonin-induced cAMP accumulation incubated f...More data for this Ligand-Target Pair