BDBM50568949 CHEMBL4875011
SMILES Cc1ccc(c(Cl)c1)-c1cc2cnc(Nc3cccc(c3)S(C)(=O)=O)nc2n(C)c1=O
InChI Key InChIKey=OMLZCXJVYHKTKX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50568949
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair