BDBM505700 (S)-8-chloro-4-((3-chloro-4- fluorophenyl)amino)-6-(((1-(1- ethylpiperidin-4-yl)-1H-1,2,3-triazol- 4-yl)(pyridin-3-yl)methyl)amino)- quinoline-3-carbonitrile::US11066414, Compound 362

SMILES CCN1CCC(CC1)N1NNC(=C1)[C@@H](Nc1cc(Cl)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1)c1cccnc1

InChI Key InChIKey=YBBJALLRFJWXCC-PMERELPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505700   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM505700((S)-8-chloro-4-((3-chloro-4- fluorophenyl)amino)-6...)
Affinity DataIC50:  3.98E+3nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM505700((S)-8-chloro-4-((3-chloro-4- fluorophenyl)amino)-6...)
Affinity DataIC50:  1nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent