BDBM50570559 CHEMBL4868687

SMILES COC(=O)C(=N/Nc1ccc(C)cc1)\C(=O)C(F)(F)F

InChI Key InChIKey=WBTOVOOOKUVTED-MFOYZWKCSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50570559   

TargetLiver carboxylesterase(Sus scrofa)
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataKi:  14nMAssay Description:Competitive inhibition of porcine liver carboxylesterase by double reciprocal Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataKi:  1.01E+4nMAssay Description:Competitive inhibition of human erythrocyte AChE by double reciprocal Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataKi:  2.92E+4nMAssay Description:Competitive inhibition of equine serum BuChE by double reciprocal Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataIC50:  2.83E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylcholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataIC50:  193nMAssay Description:Inhibition of human recombinant CES2 expressed in mouse NSO cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant CES1 expressed in baculovirus infected BTI insect cells using 4-NPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase(Sus scrofa)
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50570559(CHEMBL4868687)
Affinity DataIC50:  28nMAssay Description:Inhibition of porcine liver carboxylesterase using 4-NPA as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed