BDBM50570972 CHEMBL4848359
SMILES CNC(=O)c1nc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cc(F)cc(F)c2)cc1C
InChI Key InChIKey=WFLLOUGNTSBEON-GOSISDBHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50570972
Affinity DataIC50: 40nMAssay Description:Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Hibercell
Curated by ChEMBL
Hibercell
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair