BDBM50571052 CHEMBL4869889

SMILES [#6]-n1nc(-[#6]-c2nnc(-[#16]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c3ccc(Cl)cc3Cl)n2-[#6]-[#6]-[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])c2ccccc2c1=O

InChI Key InChIKey=MZIJQTGOQIVPQH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571052   

TargetInterleukin-15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571052(CHEMBL4869889)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50571052(CHEMBL4869889)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL2-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-15(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571052(CHEMBL4869889)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571052(CHEMBL4869889)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed