BDBM50571056 CHEMBL4863838

SMILES [#6]-n1c(-[#6]-c2nn(-[#6]-[#6]-[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])c(=O)c3ccccc23)nnc1-[#16]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-c1ccc(Cl)cc1Cl

InChI Key InChIKey=UWFBQOBRCWVTNY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571056   

TargetInterleukin-15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571056(CHEMBL4863838)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of RLI incubated for 30 mins followed by RLI addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50571056(CHEMBL4863838)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL2-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-15(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571056(CHEMBL4863838)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL-15-induced STAT3 phosphorylation in human NK92 cells incubated for 30 mins followed by IL-15 stimulation and measured after 1 hr by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50571056(CHEMBL4863838)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IL-15 in mouse 32Dbeta cells assessed as decrease in cell growth in presence of IL2 incubated for 30 mins followed by IL2 addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed