BDBM50571462 CHEMBL4849786::US11685734, Example 88
SMILES CO[C@@H]1CCN([C@H]1Cc1ccccc1)c1cc(cc(=O)[nH]1)N1CCOCC1
InChI Key InChIKey=GNYNSVCRNXNYNU-RBUKOAKNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50571462
Affinity DataKi: 23nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:ATM: Recombinant, full length human FLAG-tagged ATM activity (Eurofins 14-933) was measured in an ELISA for p53 S15 phosphorylation, in a 384 well V-...More data for this Ligand-Target Pair