BDBM50573506 CHEMBL4861833

SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=GVUHDEMSKMOPHW-WKOQKXSESA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50573506   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50573506(CHEMBL4861833)
Affinity DataIC50:  14nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50573506(CHEMBL4861833)
Affinity DataIC50:  69nMAssay Description:Inhibition of human recombinant CDK12/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50573506(CHEMBL4861833)
Affinity DataIC50:  633nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50573506(CHEMBL4861833)
Affinity DataIC50:  49nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 13/Cyclin-K(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50573506(CHEMBL4861833)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed