BDBM50574654 CHEMBL4870906

SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=OXAVSEDRFGCUAY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574654   

TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50574654(CHEMBL4870906)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid 2-hydroxylase(Human)
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50574654(CHEMBL4870906)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amyl as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50574654(CHEMBL4870906)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA as substrate by microplate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed