BDBM50575298 CHEMBL4859723

SMILES Cc1cc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n(C)n1

InChI Key InChIKey=WPMGEVLWMIBBAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575298   

TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575298(CHEMBL4859723)
Affinity DataIC50:  4nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575298(CHEMBL4859723)
Affinity DataIC50:  4nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed