BDBM50575345 CHEMBL4848347
SMILES CC(=O)N1CCN(CC1)[C@H]1C[C@H](C1)n1cc(-c2cccc(O)c2)c2c(N)ncnc12
InChI Key InChIKey=HDWGWERBFXSKLX-CALCHBBNSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50575345
TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hr...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of RET (658 to 1072) (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
The Genomics Institute Of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tel fused KDR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell p...More data for this Ligand-Target Pair