BDBM50575553 CHEBI:18315::PYRROLOQUINOLINE QUINONE

SMILES OC(=O)c1cc2c([nH]1)-c1c(cc(nc1C(=O)C2=O)C(O)=O)C(O)=O

InChI Key InChIKey=MMXZSJMASHPLLR-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

PDB links: 42 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50575553   

TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50575553(CHEBI:18315 | PYRROLOQUINOLINE QUINONE)
Affinity DataKi:  332nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50575553(CHEBI:18315 | PYRROLOQUINOLINE QUINONE)
Affinity DataIC50:  582nMAssay Description:Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as reduction in dynamic mass redistribution response in presence of GPR35 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50575553(CHEBI:18315 | PYRROLOQUINOLINE QUINONE)
Affinity DataEC50:  71nMAssay Description:Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as dynamic mass redistribution response by DMR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50575553(CHEBI:18315 | PYRROLOQUINOLINE QUINONE)
Affinity DataIC50:  30nMAssay Description:Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed