BDBM50575689 CHEMBL4850670

SMILES O=C(CCC1NC(=O)NC1=O)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=GYKPTYVBUHPMNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50575689   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50575689(CHEMBL4850670)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50575689(CHEMBL4850670)
Affinity DataIC50:  715nMAssay Description:Inhibition of human recombinant ADAMTS-4 (AA1 to 520) assessed as cleavage of fluorescent substrate using as TBIS-1 substrate incubated for 180 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 1(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50575689(CHEMBL4850670)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant ADAMTS-1 (AA253 to 734) assessed as cleavage of fluorescent substrate using 5(6)-fluorescein-NH-AELQGRPISIAK-5(6)-TAM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed