BDBM50576165 CHEMBL4875540
SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)NC(=O)CCCC(=O)N[C@@H]1CC[C@@]2(C)[C@]([H])(C[C@H](O)[C@@]3([H])[C@]4([H])CC[C@]([H])([C@H](C)CCC(=O)NCCS(O)(=O)=O)[C@@]4(C)CC[C@]23[H])C1)[C@H](C)CCC(=O)NCCS(O)(=O)=O
InChI Key InChIKey=HMRCFYLIRXYMLL-DUSUIUHSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50576165
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells after 2 hrsMore data for this Ligand-Target Pair
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of human NTCP residues (157 to 165) replaced with monkey NTCP -mediated [3H]-TCA uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair