BDBM50576167 CHEMBL4862057

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)n1cc(CC[C@@H](C)[C@@]2([H])CC[C@@]3([H])[C@]4([H])[C@@H](O)C[C@]5([H])C[C@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]23C)nn1)[C@H](C)CCC(=O)NCCS(O)(=O)=O

InChI Key InChIKey=JAVOHSUERRODGN-TXGGOJPRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50576167   

TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50576167(CHEMBL4862057)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells in presence of 20 % FBSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50576167(CHEMBL4862057)
Affinity DataIC50:  25nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells pretreated for 2 hrs followed by [3H]-TCA addition in absence of FBSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50576167(CHEMBL4862057)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells in presence of 50 % FBSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed