BDBM50576673 CHEMBL4849769

SMILES COc1cncc2O[C@]3([C@@H]([C@@H](CO)[C@H](CN4CCOCC4)[C@@]3(O)c12)c1ccccc1)c1ccc(Br)cc1

InChI Key InChIKey=IFRZKYZIXROIRF-PUOQHSKASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576673   

TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Effector Therapeutics

Curated by ChEMBL
LigandPNGBDBM50576673(CHEMBL4849769)
Affinity DataIC50:  32nMAssay Description:Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring short 5'-UTR of tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Effector Therapeutics

Curated by ChEMBL
LigandPNGBDBM50576673(CHEMBL4849769)
Affinity DataIC50:  10nMAssay Description:Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring highly structured 5'-UTR of c-MycMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed