BDBM50576849 CHEMBL4876008

SMILES Cl.CCOC(=O)[C@@H](Cc1cn(C)c2ccccc12)NC(=O)[C@@H](N)CC(C)C

InChI Key InChIKey=PXFDVONNVFXYEP-MCJVGQIASA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50576849   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50:  5.00E+3nMAssay Description:Direct inhibition of CYP3A4 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP2D6 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of CYP2C19 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2B6 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C8 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of OCT2 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of OATP1B3 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of OAT3 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPOU domain, class 2, transcription factor 1(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed