BDBM50578114 CHEMBL4862717

SMILES NC1CCN(CC1)c1c(NC(=O)c2cn3ccccc3n2)cncc1-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=KEIGDQLHVNXHKG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578114   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50578114(CHEMBL4862717)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells with holding potential -80 mV incubated for 5 mins by patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50578114(CHEMBL4862717)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed