BDBM5058 1,2,4-Oxadiazole Analogue 4c::4-[(2S)-2-{[(1S)-3-carbamoyl-1-(3-{[4-(propan-2-yl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid

SMILES CC(C)c1ccc(Cc2noc(n2)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(C)=O)cc1

InChI Key InChIKey=SPHWONUKLUPCHU-GOTSBHOMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5058   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5058(1,2,4-Oxadiazole Analogue 4c | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  9.60E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5058(1,2,4-Oxadiazole Analogue 4c | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  3.60E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed