BDBM50581019 CHEMBL5089949

SMILES COC(=O)c1ccc(CCNC(=N)N\N=C\c2c[nH]c3c(C)cc(cc23)C#N)cc1

InChI Key InChIKey=XIVYUSRYHWXGLX-UVHMKAGCSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50581019   

TargetRelaxin-3 receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581019(CHEMBL5089949)
Affinity DataKi:  69nMAssay Description:Displacement of [125I]R3/I5 from human RXFP3 expressed in human CHO-K1 cells incubated for 1 hr by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRelaxin-3 receptor 2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581019(CHEMBL5089949)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human RXFP4 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRelaxin-3 receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581019(CHEMBL5089949)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRelaxin-3 receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50581019(CHEMBL5089949)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as beta arrestin-2 recruitment measured after 4 hrs by beta-galactosidase ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed