BDBM50582231 CHEMBL5092697

SMILES CC(F)(F)CNC(=O)[C@@H](CC(F)(F)F)c1ccc2[nH]c(nc2c1F)[C@@H](NC(=O)c1nonc1C1CC1)C1CCC(F)(F)CC1

InChI Key InChIKey=IJCMVIBDWCAJAI-KXBFYZLASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582231   

TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582231(CHEMBL5092697)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed