BDBM50582669 CHEMBL5092170
SMILES Cn1ccc(n1)-c1cc(Cl)c(Cl)c2[nH]c3CCN(Cc3c12)C(=O)CNC(=O)Cc1ccco1
InChI Key InChIKey=AJZDPINAQHQTPL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50582669
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Affinity DataIC50: 7.17E+3nMAssay Description:Inhibition of human cGAS expressed in THP1-Dual cells transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced ac...More data for this Ligand-Target Pair