BDBM50582674 CHEMBL5092231
SMILES CC(=O)OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1cccc(Cl)c1C=O
InChI Key InChIKey=AHDNSKBLJPNNKH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50582674
TargetCyclic GMP-AMP synthase(Mus musculus)
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced acti...More data for this Ligand-Target Pair
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Shanghai Institute Of Materia Medica (Simm)
Curated by ChEMBL
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of human cGAS expressed in THP1-Dual cells transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced ac...More data for this Ligand-Target Pair