BDBM50582802 CHEMBL5092293

SMILES C[C@@H]1CN(C[C@H](CN2CC3(C2)OCc2cc(ccc32)N2CC3(CN(C)C3)C2)O1)c1ccc(C#N)n2nccc12

InChI Key InChIKey=QOLBPJHTZXJFLH-BWKNWUBXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582802   

TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582802(CHEMBL5092293)
Affinity DataIC50:  5nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue hTLR7 cells assessed as inhibition of TLR7 by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582802(CHEMBL5092293)
Affinity DataIC50:  32nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue hTLR9 cells assessed as inhibition of TLR9 by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582802(CHEMBL5092293)
Affinity DataIC50:  40nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TLR8 by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed