BDBM50582917 CHEMBL5089945

SMILES Cc1ccc(cc1)-c1nc(SCC(=O)c2ccccc2)nc(Nc2ccc(cc2)S(N)(=O)=O)c1C#N

InChI Key InChIKey=AELXTZHCYXOOKT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50582917   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582917(CHEMBL5089945)
Affinity DataKi:  3nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582917(CHEMBL5089945)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582917(CHEMBL5089945)
Affinity DataKi:  9.70nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582917(CHEMBL5089945)
Affinity DataKi:  406nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed