BDBM50586724 CHEMBL5082666

SMILES [O-][N+](=O)CC(c1c([nH]c2ccccc12)-c1ccsc1)c1ccccc1

InChI Key InChIKey=NCOQFHIDDWOEMQ-UHFFFAOYSA-N

Data  1 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50586724   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50586724(CHEMBL5082666)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid scintillation spectrometry ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50586724(CHEMBL5082666)
Affinity DataEC50:  320nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as beta-arrestin 2 recruitment incubated for 90 mins by PathH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50586724(CHEMBL5082666)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of CB1 receptor in MF1 mouse vas deferens assessed as inhibition of AEA-induced electrically evoked vas deferens contr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50586724(CHEMBL5082666)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in [35S]GTPgammaS binding incubated for 30 mins by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50586724(CHEMBL5082666)
Affinity DataEC50:  87nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP production incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed