BDBM50586944 CHEMBL5090821
SMILES CS(=O)(=O)Nc1ccc(CNC(=O)c2ccc3n(Cc4cccc(F)c4)ccc3c2)c(c1)C(F)(F)F
InChI Key InChIKey=WWVQEDHOKLQQAY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50586944
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe-University
Curated by ChEMBL
Goethe-University
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Partial agonist activity at recombinant sGSF-PPARgamma (unknown origin) assessed as reduction in rosiglitazone induced CBP-1 recruitment incubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of N-terminal His-tagged mouse sEH (2 to 554 residues) expressed in Escherichia coli Rosetta2 (DE3) assessed as reduction in 6-methoxy-2-n...More data for this Ligand-Target Pair