BDBM50587249 CHEMBL5094795
SMILES CCc1c([nH]c(C)c1C(C)=O)C(=O)Nc1cccc(\C=C\C(=O)NO)c1
InChI Key InChIKey=GVORXNGLOKKWIC-CMDGGOBGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50587249
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human BRD3 domain 1 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human BRD2 domain 2 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.70E+3nMAssay Description:Binding affinity to human BRD2 domain 1 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.50E+3nMAssay Description:Binding affinity to human BRD4 domain 1 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataIC50: 149nMAssay Description:Inhibition of human HDAC3 assessed as target activity using fluorogenic substrate ZMAL for 90 min by microplate reader at 355nmMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant HDAC1 assessed as fluorescence using fluorogenic substrate ZMAL incubated for 90 min by microplate readerMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human BRD3 domain 2 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human BRD7 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Inhibition of human HDAC2 assessed as target activity using fluorogenic substrate ZMAL for 90 min by microplate reader at 355nmMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HDAC6 assessed as fluorescence using fluorogenic substrate ZMAL incubated for 90 min by microplate readerMore data for this Ligand-Target Pair