BDBM50587785 CHEMBL5178368

SMILES CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1

InChI Key InChIKey=CZZCAOGIEGXMBZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50587785   

TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  2nMAssay Description:Inhibition of haspin (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human PIM1 expressed in bacterial expression system using histone H1 as substrate measured after 30 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  119nMAssay Description:Inhibition of human recombinant JAK3 expressed in baculovirus sf9 insect cells using GGEEEEYFELVKKKK as substrate measured after 30 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate measured after 3...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  99nMAssay Description:Inhibition of human recombinant CK1 epsilon expressed in baculovirus in sf9 insect cells using RRKHAAIGSpAYSITA as substrate in presence of ATP measu...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in bacterial expression system using histone H1 as substrate in presence of ATP at measured after ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  162nMAssay Description:Inhibition of human recombinant ABL1 expressed in baculovirus sf9 insect cells using EAIYAAPFAKKK as substrate measured after 30 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In DepthDetails PubMed