BDBM50588768 CHEMBL5175256
SMILES [2H]C([2H])([2H])NC(=O)c1cncc(c1)-c1cnn2cc(-c3ccn(n3)C(C)C)c(N[C@H]3CCOC3)nc12
InChI Key InChIKey=XGJBIMKIGAOMPJ-JBKGLDERSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50588768
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST tagged recombinant human FGFR2 (400 to 821 residues) expressed in an Sf9 infected baculovirus expression system using bi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant human FGFR1 using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition an...More data for this Ligand-Target Pair