BDBM50588796 CHEMBL5197792
SMILES COc1cc2c(Oc3ccc(Nc4nn(C)cc4C(=O)NC4CCCCC4)cc3F)ccnc2cc1OCCCN1CCOCC1
InChI Key InChIKey=QBRQTJMZEYORSP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50588796
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant AXL (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRB (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 29nMAssay Description:Binding affinity to CSF1R (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to DDR1 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to EPHB6 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 14nMAssay Description:Binding affinity to FLT1 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 2.5nMAssay Description:Binding affinity to FLT3 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding affinity to FLT4 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 2.60nMAssay Description:Binding affinity to KIT (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 880nMAssay Description:Binding affinity to LOK (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to MAP4K5 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 560nMAssay Description:Binding affinity to MERTK (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to MET (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to MSTIR (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 2.30nMAssay Description:Binding affinity to PDGFRB (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataKd: 600nMAssay Description:Binding affinity to RET (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.740nMAssay Description:Binding affinity to TIE1 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 950nMAssay Description:Binding affinity to TIE2 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 156nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 0.260nMAssay Description:Binding affinity to AXL (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair