BDBM50589954 CHEMBL5177079
SMILES Fc1ccc(NC(=O)Cc2ccn(n2)-c2ccc(C#N)c(c2)C(F)(F)F)cc1
InChI Key InChIKey=NHPPXRZVKDOUPD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50589954
Affinity DataIC50: 120nMAssay Description:Antagonist activity at androgen receptor (unknown origin) in human LNCap-ARR2PB-eGFP cells by measuring fluorescence intensity measured after 3 days ...More data for this Ligand-Target Pair
Affinity DataKd: 1.01E+4nMAssay Description:Binding affinity to full length androgen receptor (unknown origin) assessed as dissociation constant at 5 uM measured after 15 mins by biolayer inter...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Antagonist activity at androgen receptor F876L/T877A mutant in human PC-3 cells assessed as inhibition of transcriptional activity measured after 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Antagonist activity at androgen receptor F877L/T877A dual mutant (unknown origin) expressed in PC-3 cells assessed as inhibition of transcriptional a...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Antagonist activity at androgen receptor F877L mutant in human PC-3 cells assessed as inhibition of transcriptional activity measured after 24 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Antagonist activity at androgen receptor F877L mutant (unknown origin) expressed in PC-3 cells assessed as inhibition of transcriptional activity mea...More data for this Ligand-Target Pair