BDBM50589973 CHEMBL5184569

SMILES OC(=O)CN(CC1c2ccccc2C=Cc2ccccc12)C(=O)NS(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=XJBCYCWPLLYLPI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50589973   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589973(CHEMBL5184569)
Affinity DataKi:  9nMAssay Description:Inhibition of human MMP-2 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589973(CHEMBL5184569)
Affinity DataKi:  13nMAssay Description:Inhibition of human MMP-8 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589973(CHEMBL5184569)
Affinity DataIC50:  21nMAssay Description:Inhibition of Clostridium histolyticum CoLH using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated for 10 mins by fluorescence spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed