BDBM50589973 CHEMBL5184569
SMILES OC(=O)CN(CC1c2ccccc2C=Cc2ccccc12)C(=O)NS(=O)(=O)c1ccc(F)cc1
InChI Key InChIKey=XJBCYCWPLLYLPI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50589973
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)
Curated by ChEMBL
Helmholtz Center For Infection Research (Hzi)
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of human MMP-2 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)
Curated by ChEMBL
Helmholtz Center For Infection Research (Hzi)
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of human MMP-8 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)
Curated by ChEMBL
Helmholtz Center For Infection Research (Hzi)
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of Clostridium histolyticum CoLH using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated for 10 mins by fluorescence spe...More data for this Ligand-Target Pair