BDBM50590270 CHEMBL5181770

SMILES Cc1cc(Br)cc2c1nc(CSc1ncccn1)[nH]c2=O

InChI Key InChIKey=UYAVGZOEYLNVKI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590270   

TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590270(CHEMBL5181770)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590270(CHEMBL5181770)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590270(CHEMBL5181770)
Affinity DataIC50:  800nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed