BDBM50590271 CHEMBL5198711
SMILES Cc1cc(C)c2nc(CSc3ncccn3)[nH]c(=O)c2c1
InChI Key InChIKey=JNLILESBBKKTIC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50590271
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Initial Therapeutics
Curated by ChEMBL
Initial Therapeutics
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair