BDBM50590284 CHEMBL5192316

SMILES O=C(Nc1ncc(s1)-c1ccc(cc1)C#C)[C@H]1CCN(C1)C#N

InChI Key InChIKey=ICEKJWVSDFOADH-AWEZNQCLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590284   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590284(CHEMBL5192316)
Affinity DataIC50:  600nMAssay Description:Inhibition of GST-tagged recombinant UCHL1 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590284(CHEMBL5192316)
Affinity DataIC50:  830nMAssay Description:Inhibition of FLAG-tagged UCHL1 (unknown origin) expressed in CAL-51 cells using HA-Ub-VME as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50590284(CHEMBL5192316)
Affinity DataIC50: >10nMAssay Description:Inhibition of GST-tagged recombinant UCHL3 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed