BDBM50590370 K-0706::K0706::Sco-088::VODOBATINIB::Vodobatinib
SMILES Cc1ccc(cc1C#Cc1cnc2ccccc2c1)C(=O)NNC(=O)c1c(C)cccc1Cl
InChI Key InChIKey=ZQOBVMHBVWNVBG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50590370
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of wild type BCR-ABL phosphorylation in mouse BaF3 cells incubated for 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of BCR-ABL T315I mutant phosphorylation in mouse BaF3 cells incubated for 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 165nMAssay Description:Inhibition of BCR-ABL E255V mutant phosphorylation in mouse BaF3 cells incubated for 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair